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- W2364264552 abstract "Objective To standardize the methods of recording and analyzing the sleep electroencephalogram(EEG)of rats and to explore the related factors affecting the EEG results of sleeping rats.Methods Under the conditions of controlling temperature,humidity,light automatically and electromagnetic shielding,the technology of chronic electrode implantation was used to record the cortical EEG in free-moving rats,and to observe the effects caused by gender and weight of the experimental rats on sleep time and sleep phase.After this experimental method was standardized,the different properties between the drug sleep evoked by Diazepam and the physiological sleep were compared to verify the reliability of this experimental method.Results Both gender and weight influenced total sleep time (TST),slow wave sleepⅡ(SWS_2)time,rapid eye movement sleep(REM)time of rats markedly.Compared with physiological sleep,the drug sleep caused by Diazepam had prolonged TST,shortened total time,mean duration,reduced frequency of SWS_2,and shortened mean duration and increased frequency and prolonged total time of REM.The results are in accordance with the related references.Conclusion Gender and weight of experimental animals influence to some extent the results of recording and analyzing the sleep EEG of rats." @default.
- W2364264552 created "2016-06-24" @default.
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- W2364264552 date "2006-01-01" @default.
- W2364264552 modified "2023-09-23" @default.
- W2364264552 title "Related factors influencing EEG results of sleeping rats" @default.
- W2364264552 hasPublicationYear "2006" @default.
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