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- W2364270621 abstract "Objective The aim of this study was to evaluate the efficacy and safety of aripirazole in the treatment of childhood patients with first-episode schizophrehia.Methods 60 patients with first-episode schizophrenia(age14)were included in this 8 week open clinical study.The positive and negative symptom scale(PANSS)was used to evaluate the severity and the improvement of mental symptoms,The Treatment Emergent side Effect scale(TESS)and laboratory tests were used to assess the adverse effects.Scales were evaluated at baseline and the end of weeks1、2、4、6,8.Descriptive analsysis and paired t-test were performed in statistical analysis.Results 60 valid cases were collected,among the 60 patients,20.0%met the criteria of complete relief,30.0%significantly improved,30.0%improved,and 20.0%got no change.significant differences existed in total PANSS scores and factor scores of PANSS after 8 week treatment of aripirazole,Aripirazole showed good effect on the positive,negative as well as general psychopathological symptoms of childhood patients with first-episode schizophrenia.No serious adverse events were found during the treatment.Conclusion This study suggests that aripirazole is an effective and safe antipsychotic in the treatment of childhood patients with first-episode schizophrenia." @default.
- W2364270621 created "2016-06-24" @default.
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- W2364270621 date "2008-01-01" @default.
- W2364270621 modified "2023-09-25" @default.
- W2364270621 title "An open-label Clinical trial of Aripiprazole in the treatment of 60 childhood patients with first-episode schizophrenia" @default.
- W2364270621 hasPublicationYear "2008" @default.
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