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- W2364272925 abstract "Objective To observe the effect of nicardipine with small-dose esmolol on car-diovascular responses to tracheal extubation following intracranial surgery. Methods Forty patients undergoing intracranial surgery were randomly divided into group A receiving nicardipine 10～20 μg/kg plus esmolol 0.5～1 mg/kg at the beginning of breathing after operation, group B receiving normal saline as the control, respectively. Extubation was performed 15 minutes after the designated drug was intravenously administered. SBP, DBP, MAP and HR were observed at pre-administration, at extubation and 1, 3, 5, 10, 20 minutes after administration. Results SBP, DBP and HR was significantly lower than those of pre-administration in groupA (P0.01), at extubation and 3, 5, 10, 20 minutes after administration. SBP, DBP and HR showed no change in group B(P0 05), except 20 minutes after administration. Conclusion Nicardipine combined with a small-dose esmolol attenuates the cardiovascular responses to tracheal extubation following intracranial surgery." @default.
- W2364272925 created "2016-06-24" @default.
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- W2364272925 date "2005-01-01" @default.
- W2364272925 modified "2023-09-27" @default.
- W2364272925 title "Effect of nicardipine combined with a small-dose esmolol on cardiovascular responses to tracheal extubation following intracranial surgery" @default.
- W2364272925 hasPublicationYear "2005" @default.
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