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- W2364273368 abstract "Objective To observe the serum level of angiopoietin-2(Ang-2)in T2DM patients,and investigate the correlation between Ang-2and microvascular complications. Methods Totally 64T2DM patients were involved,28cases without chronic kidney disease(CKD)were in the T2DM group,and 36patients with CKD in the CKD group.The normal control(NC)group included 23healthy subjects. Results the Ang-2level was higher in the CKD group than in the T2DM group(2.38 vs 1.12ng/ml,P0.01),the Ang-2level in the T2DM group was higher than in the NC group(1.12 vs 0.46ng/ml,P0.01),the Ang-2level was higher in the proliferative diabetic retinopathy(DR)patients than in the non-proliferative DR patients(2.83 vs 1.96ng/ml,P0.01),and the Ang-2level in the non-proliferative DR patients was higher than in the patients without DR(1.96 vs 1.08ng/ml,P0.05).Ang-2was positively correlated with high-sensitivity C-reactive protein(hsC-RP)(r=0.63,P0.01)and UAlb(r=0.29,P0.05). Conclusion T2DM patients have an elevated Ang-2level,which is positively correlated with hsC-RP,proteinuria,DR,and intima-media thickness.Ang-2 may be a potential biomarker of renal and retina microvascular involvement in T2DM patients." @default.
- W2364273368 created "2016-06-24" @default.
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- W2364273368 date "2013-01-01" @default.
- W2364273368 modified "2023-09-24" @default.
- W2364273368 title "Changes and clinical significance of serum level of angiopoietin-2 in T2DM patients" @default.
- W2364273368 hasPublicationYear "2013" @default.
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