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- W2364274701 abstract "Objective The aim of this study is to investigate the role of plasma cytokines IL-2,IFN-γ,IL-4 and TGF-β1 in the pathogenesis of children with Henoch-Schonlein purpura( HSP). Methods Plasma levels of cytokine IL-2,IL-4 and IFN-γ were detected by Luminex-100 and TGF-β1 was analyzed by ABC-ELISA in 46 patients with HSP in the acute phase and 30 healthy children( control group). Results The levels of IL-2 and IFN-γ in the HSP patients were lower than that in the control group while levels of IL-4 and TGF-β1 in the HSP patients were higher than that in the control group. The differences were statistically significant( P 0. 01). Conclusion There is cytokine disorder in children with HSP. This may be the molecular biological basis for the pathogenesis of the disease." @default.
- W2364274701 created "2016-06-24" @default.
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- W2364274701 date "2014-01-01" @default.
- W2364274701 modified "2023-09-28" @default.
- W2364274701 title "The changes of plasma IL-2,IFN-γ,IL-4 and TGF-β1 in children with Henoch-Schonlein purpura and their clinical significance" @default.
- W2364274701 hasPublicationYear "2014" @default.
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