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- W2364278212 abstract "The brainstem ischemic injuries were produced by the occlusion of the basilar artery for 6 h in dogs. Gypenoside (150 mg ?kg-1)were intradudinally given at 3 h before the occlusion. We discovered that gypenoside alleviated the ischemic neuronal damage (histopathologically evaluated by the light and electronic microscope), ameliorated the abnormal changes of brainstem auditory evoked potentials (BAEP) (F0. 01), inhabited the phos-pholipase A2( PLA2)activation induced by the ischemia (P0. 01) and intensified the superoxide dismutase (SOD) activity (P0.01). The results suggest that gypenoside has the protective effects on brainstem ischemic injuries and its mechanism may involve its capacity to antagonize the Ca2+ and free radicals related injuries." @default.
- W2364278212 created "2016-06-24" @default.
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- W2364278212 date "1996-01-01" @default.
- W2364278212 modified "2023-09-28" @default.
- W2364278212 title "Protective effect of gypenoside on brainstem ischemic injuries in dogs" @default.
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