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- W2364278881 abstract "Objective To establish and evaluate a rat model of metabolic syndrome induced by high fat and salt diet.Methods Wistar rats,aged 8 weeks,were given routine diet(control) and high fat and salt diet(model),10 animals in each group.Then the body weights,blood pressure and blood glucose were measured every 2-4 weeks;24 weeks later,an intraperitoneal glucose tolerance test and a hyperinsulinemic euglycemic clamp test were performed,and the plasma lipids,the amount of fat around visceral organs and body length were measured.Results In the model group,(i) the body weight,visceral fat,blood pressure,insulin and triglycerol levels were all significantly increased compared to the control,and(ii) significant insulin resistance occurred.Conclusions High fat and salt diet given to rats could induce a metabolic syndrome,which corresponds or is analogous to the clinical metabolic syndrome." @default.
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- W2364278881 date "2007-01-01" @default.
- W2364278881 modified "2023-09-27" @default.
- W2364278881 title "Establishment of an Animal(Wistar Rats) Model of Metabolic Syndrome and Analysis on its Features" @default.
- W2364278881 hasPublicationYear "2007" @default.
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