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- W2364279819 abstract "Objective:To investigate the effect of Shenmai Injection (SMI) on the activity of L-type Ca2+ channels in airway smooth muscle (ASM) of rat model with asthma. Methods: With conventional whole-cell patch clamp technique, changes of Ca2+ channel activity in ASM cells from asthmatic rats and the effect of SMI administration in vivo on it were observed. Results: ① Ca2+ channel activity in ASM cells from asthmatic rats was significantly enhanced compared with that from controls.② SMI significantly suppressed the enhanced activity of L-type calcium channels in rat ASM cells under asthmatic conditions (P0.05). Conclusion: SMI could significantly downregulate the activity of Ca2+ channel in rat model with asthma, and might have some preventive and therapy effect on asthma." @default.
- W2364279819 created "2016-06-24" @default.
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- W2364279819 date "2008-01-01" @default.
- W2364279819 modified "2023-09-23" @default.
- W2364279819 title "Effect of Shenmai Injection on the Activity of Calcium Channels in Airway Smooth Muscle Cells of Rat Model With Asthma" @default.
- W2364279819 hasPublicationYear "2008" @default.
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