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- W2364282390 abstract "Postinfectious irritable bowel syndrome(PI-IBS) is a common clinical type of irritable bowel syndrome (IBS).Visceral hypersensitivity,which is a core mechanism of PI-IBS,might be related to sensitization of gastrointestinal afferent nerve and dysfunction of nerve negatively modulating visceral pain response.Mucosal mast cells participate in the regulation of visceral hypersensitivity through their degranulation products such as 5-hydroxytryptamine(5-HT),and relevant preparations have already been used in curing IBS,while their efficacy remains uncertain.Therefore,in-depth research on functional changes of mucosal mast cells and their roles in visceral hypersensitivity in PI-IBS would provide new insights into pathophysiological mechanism and clinical treatment of PI-IBS." @default.
- W2364282390 created "2016-06-24" @default.
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- W2364282390 date "2011-01-01" @default.
- W2364282390 modified "2023-09-24" @default.
- W2364282390 title "Research Progress of Mucosal Mast Cells in Mechanism of Visceral Hypersensitivity in Postinfectious Irritable Bowel Syndrome" @default.
- W2364282390 hasPublicationYear "2011" @default.
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