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- W2364285417 abstract "Objective To investigate the Influence of temperature and time before centrifugation of specimens for routine coagulation testing.MethodsSixty specimens from patients were collected.Three evacuated tubes containing 0.109 mol/Lbuffered trisodium citrate were sequentially collected from each patient.These three tubes were mixed,pooled and divided into seven identical aliquots.The first aliquot was immediately centrifuged according to the standard protocol [3 000 r/min for 10 min at room temperature(RT)] and analyzed.The other aliquots were left for 3,6 and 12 h,respectively,at RT or 4℃,and then centrifuged and analyzed.ResultsCompared with those obtained on the reference specimen,prolongations were observed for APTT in all the samples.Such differences exceeded the statistically analytical range for 12 h.A reduction was observed for PT and fibrinogen in uncentrifuged specimens stored at RT for 3 and 6 h,but have no statistical significance.D-dimer had no significant change in all specimens.Conclusion6-h storage of uncentrifuged specimens at either RT or 4℃ may still be suitable to achieve results of routine coagulation testing comprised within the analytical quality specifications for desirable bias." @default.
- W2364285417 created "2016-06-24" @default.
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- W2364285417 date "2011-01-01" @default.
- W2364285417 modified "2023-09-26" @default.
- W2364285417 title "Study on the influence of temperature and time before centrifugation of specimens for routine coagulation testing" @default.
- W2364285417 hasPublicationYear "2011" @default.
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