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W2364291007 abstract "Objective To investigate the distribution feature of G3261A polymorphism of γ-glutamylcarboxylase (GGCX) gene in Chinese population.Methods Genome DNA samples of 273normal subjects were extracted by phenol-chloroform method from peripheral blood.A PCR/DHPLC genotyping assay was used to detect the genotypes of GGCX G3261A.Results Among 273 individuals ,the numbers of GG,GA and AA genotype were 110 ,138 and 25 ,with the frequencies of 40.29 %,50.55 % and 9.16 %,respectively. The frequencies of G and A allele were 65.57 % and 34.43 %,respectively.Conclusion The allelic and genotypic frequency distribution of GGCX G3261 A polymorphismin Chinese population are determined ,which is helpful for the further study of the association of GGCX G3261A polymorphism with individual dose requirement of warfarin." @default.
W2364291007 created "2016-06-24" @default.
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W2364291007 date "2010-01-01" @default.
W2364291007 modified "2023-09-28" @default.
W2364291007 title "Detection of GGCX G3261A gene polymorphism in Chinese population" @default.
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