Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364294902> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2364294902 abstract "Objective To evaluate the expression of hypoxia inducible factor-1α(HIF-1α) after spinal cord ischemic reperfusion injury(SCII) in the rat.Methods Experimental SCII models in rat were established and the expression of HIF-1α in spinal cord tissue was detected by Western blot and immunohistochemistry analysis.ResultsThe expression of HIF-1α in the whole spinal cord was increased at 8 h after SCII,peaked at 24 h,declined at 3 d,and was decreased significantly at 5 d after reperfusion.The expression area of HIF-1α in gray matter at 8 h,12 h,24 h,3 d,5 d was(211.39±5.58) μm2,(184.53±6.56) μm2,(167.39±5.76) μm2,(198.44±3.98) μm2 and(228.39±2.87) μm2,respectively.They were significantly higher than those of control group(P0.05).Positive immunostaining of HIF-1α was mostly observed surrounding the central canal of the gray matter and in the frontal horn and posterior horn.HIF-1α was found to express weakly in the white matter,but stronger in the posterior funiculus of the white matter at 24 h and 3 d after reperfusion.Expression of HIF-1α in gray matter was(238.15±6.87) μm2 and(236.87±7.41) μm2 and significantly higher than that of control group(P0.05).Neurons and astrocytes in the gray matter and neuroglia cells in the white matter showed strong expression of HIF-1α.ConclusionExpression of HIF-1α in rat SCII model was changed sequentially,so HIF-1α may play an important role in the adaptive response for SCII." @default.
- W2364294902 created "2016-06-24" @default.
- W2364294902 creator A5074481568 @default.
- W2364294902 date "2013-01-01" @default.
- W2364294902 modified "2023-09-23" @default.
- W2364294902 title "Sequential changes of hypoxia-inducible factor 1 alpha in the rat spinal cord ischemic reperfusion injury" @default.
- W2364294902 hasPublicationYear "2013" @default.
- W2364294902 type Work @default.
- W2364294902 sameAs 2364294902 @default.
- W2364294902 citedByCount "0" @default.
- W2364294902 crossrefType "journal-article" @default.
- W2364294902 hasAuthorship W2364294902A5074481568 @default.
- W2364294902 hasConcept C104317684 @default.
- W2364294902 hasConcept C105702510 @default.
- W2364294902 hasConcept C126838900 @default.
- W2364294902 hasConcept C142724271 @default.
- W2364294902 hasConcept C143409427 @default.
- W2364294902 hasConcept C169760540 @default.
- W2364294902 hasConcept C178790620 @default.
- W2364294902 hasConcept C185592680 @default.
- W2364294902 hasConcept C204232928 @default.
- W2364294902 hasConcept C2776415932 @default.
- W2364294902 hasConcept C2778013878 @default.
- W2364294902 hasConcept C2778334475 @default.
- W2364294902 hasConcept C2780775167 @default.
- W2364294902 hasConcept C2781192897 @default.
- W2364294902 hasConcept C4224716 @default.
- W2364294902 hasConcept C540031477 @default.
- W2364294902 hasConcept C55493867 @default.
- W2364294902 hasConcept C71924100 @default.
- W2364294902 hasConcept C7836513 @default.
- W2364294902 hasConcept C86803240 @default.
- W2364294902 hasConceptScore W2364294902C104317684 @default.
- W2364294902 hasConceptScore W2364294902C105702510 @default.
- W2364294902 hasConceptScore W2364294902C126838900 @default.
- W2364294902 hasConceptScore W2364294902C142724271 @default.
- W2364294902 hasConceptScore W2364294902C143409427 @default.
- W2364294902 hasConceptScore W2364294902C169760540 @default.
- W2364294902 hasConceptScore W2364294902C178790620 @default.
- W2364294902 hasConceptScore W2364294902C185592680 @default.
- W2364294902 hasConceptScore W2364294902C204232928 @default.
- W2364294902 hasConceptScore W2364294902C2776415932 @default.
- W2364294902 hasConceptScore W2364294902C2778013878 @default.
- W2364294902 hasConceptScore W2364294902C2778334475 @default.
- W2364294902 hasConceptScore W2364294902C2780775167 @default.
- W2364294902 hasConceptScore W2364294902C2781192897 @default.
- W2364294902 hasConceptScore W2364294902C4224716 @default.
- W2364294902 hasConceptScore W2364294902C540031477 @default.
- W2364294902 hasConceptScore W2364294902C55493867 @default.
- W2364294902 hasConceptScore W2364294902C71924100 @default.
- W2364294902 hasConceptScore W2364294902C7836513 @default.
- W2364294902 hasConceptScore W2364294902C86803240 @default.
- W2364294902 hasLocation W23642949021 @default.
- W2364294902 hasOpenAccess W2364294902 @default.
- W2364294902 hasPrimaryLocation W23642949021 @default.
- W2364294902 hasRelatedWork W2008559363 @default.
- W2364294902 hasRelatedWork W2354065746 @default.
- W2364294902 hasRelatedWork W2354927270 @default.
- W2364294902 hasRelatedWork W2356884642 @default.
- W2364294902 hasRelatedWork W2359188686 @default.
- W2364294902 hasRelatedWork W2360418711 @default.
- W2364294902 hasRelatedWork W2362238555 @default.
- W2364294902 hasRelatedWork W2365197483 @default.
- W2364294902 hasRelatedWork W2365730756 @default.
- W2364294902 hasRelatedWork W2366229955 @default.
- W2364294902 hasRelatedWork W2368228755 @default.
- W2364294902 hasRelatedWork W2373532273 @default.
- W2364294902 hasRelatedWork W2374105413 @default.
- W2364294902 hasRelatedWork W2379144820 @default.
- W2364294902 hasRelatedWork W2381581730 @default.
- W2364294902 hasRelatedWork W2384020393 @default.
- W2364294902 hasRelatedWork W2391785059 @default.
- W2364294902 hasRelatedWork W2501529256 @default.
- W2364294902 hasRelatedWork W2943793303 @default.
- W2364294902 hasRelatedWork W3032567933 @default.
- W2364294902 isParatext "false" @default.
- W2364294902 isRetracted "false" @default.
- W2364294902 magId "2364294902" @default.
- W2364294902 workType "article" @default.