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- W2364302327 abstract "Bcl-2 family proteins play a critical role in the regulation of apoptosis. The myeloid cell leukemia 1 (Mcl-1) is a potent anti-apoptotic Bcl-2 family member which has been reported as a resistance factor in various types of cancer. Advanced hepatocellular carcinoma (HCC) is highly treatment resistant to various chemotherapeutic modalities. Down-regulation of Mcl-1 increases chemosensitization and apoptosis of HCC cells. Therefore, targeting Mcl-1 might qualify as a promising novel approach in HCC therapy." @default.
- W2364302327 created "2016-06-24" @default.
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- W2364302327 date "2008-01-01" @default.
- W2364302327 modified "2023-10-03" @default.
- W2364302327 title "Mcl-1 gene and hepatocellular carcinoma" @default.
- W2364302327 hasPublicationYear "2008" @default.
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