Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364306561> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2364306561 endingPage "403" @default.
- W2364306561 startingPage "399" @default.
- W2364306561 abstract "Objective To determine whether the functional role of progesterone in human early pregnancy is mediated by progesterone receptor(PR) and insulin-like growth factor binding protein 1-3(IGFBP_ 1-3 ). Methods Sample collection was conducted in accordance to the principle of informed content. Decidua and villi were obtained from 48 healthy women in 5-7 weeks of pregnancy, and endometrium in mid-secretory phase was obtained as control. The serum levels of progesterone were detected by radioimmunoassay, and the expressions of IGFBP_ 1-3 and progesterone receptor were detected by immunohistochemistry (LsAB)and quantified by a computer image analysis system. Results Serum progesterone increased gradually and reached peak level in 5-6 weeks, which was significantly higher than that during the mid-secretory phase (P0.05). The expression of progesterone receptor in luminal epithelium and decidual cells had significant correlations with serum progesterone, but its expression in glandular epithelium and trophoblast cells had no correlations with serum progesterone. IGFBP_ 1-3 in luminal , glandular epithelium, and decidual cells had significant correlations with serum progesterone, but their expression in trophoblast cells had no correlations with serum progesterone. Conclusion Progesterone plays an important role in the support and maintenance of early pregnancy, and its effect may be mediated by progesterone receptor and IGFBP_ 1-3 in decidual-trophoblast interface." @default.
- W2364306561 created "2016-06-24" @default.
- W2364306561 creator A5062533184 @default.
- W2364306561 creator A5064067037 @default.
- W2364306561 creator A5067105789 @default.
- W2364306561 creator A5082647291 @default.
- W2364306561 creator A5089803732 @default.
- W2364306561 date "2006-05-01" @default.
- W2364306561 modified "2023-10-11" @default.
- W2364306561 title "[The role of progesterone in human early pregnancy is mediated by insulin-like growth factors binding protein1-3]." @default.
- W2364306561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16761418" @default.
- W2364306561 hasPublicationYear "2006" @default.
- W2364306561 type Work @default.
- W2364306561 sameAs 2364306561 @default.
- W2364306561 citedByCount "3" @default.
- W2364306561 countsByYear W23643065612016 @default.
- W2364306561 countsByYear W23643065612018 @default.
- W2364306561 countsByYear W23643065612021 @default.
- W2364306561 crossrefType "journal-article" @default.
- W2364306561 hasAuthorship W2364306561A5062533184 @default.
- W2364306561 hasAuthorship W2364306561A5064067037 @default.
- W2364306561 hasAuthorship W2364306561A5067105789 @default.
- W2364306561 hasAuthorship W2364306561A5082647291 @default.
- W2364306561 hasAuthorship W2364306561A5089803732 @default.
- W2364306561 hasConcept C121608353 @default.
- W2364306561 hasConcept C126322002 @default.
- W2364306561 hasConcept C134018914 @default.
- W2364306561 hasConcept C170493617 @default.
- W2364306561 hasConcept C172680121 @default.
- W2364306561 hasConcept C185592680 @default.
- W2364306561 hasConcept C204232928 @default.
- W2364306561 hasConcept C2776953305 @default.
- W2364306561 hasConcept C2777495146 @default.
- W2364306561 hasConcept C2779234561 @default.
- W2364306561 hasConcept C2779742232 @default.
- W2364306561 hasConcept C2780197806 @default.
- W2364306561 hasConcept C530470458 @default.
- W2364306561 hasConcept C54355233 @default.
- W2364306561 hasConcept C71924100 @default.
- W2364306561 hasConcept C84606932 @default.
- W2364306561 hasConcept C86803240 @default.
- W2364306561 hasConcept C98717036 @default.
- W2364306561 hasConceptScore W2364306561C121608353 @default.
- W2364306561 hasConceptScore W2364306561C126322002 @default.
- W2364306561 hasConceptScore W2364306561C134018914 @default.
- W2364306561 hasConceptScore W2364306561C170493617 @default.
- W2364306561 hasConceptScore W2364306561C172680121 @default.
- W2364306561 hasConceptScore W2364306561C185592680 @default.
- W2364306561 hasConceptScore W2364306561C204232928 @default.
- W2364306561 hasConceptScore W2364306561C2776953305 @default.
- W2364306561 hasConceptScore W2364306561C2777495146 @default.
- W2364306561 hasConceptScore W2364306561C2779234561 @default.
- W2364306561 hasConceptScore W2364306561C2779742232 @default.
- W2364306561 hasConceptScore W2364306561C2780197806 @default.
- W2364306561 hasConceptScore W2364306561C530470458 @default.
- W2364306561 hasConceptScore W2364306561C54355233 @default.
- W2364306561 hasConceptScore W2364306561C71924100 @default.
- W2364306561 hasConceptScore W2364306561C84606932 @default.
- W2364306561 hasConceptScore W2364306561C86803240 @default.
- W2364306561 hasConceptScore W2364306561C98717036 @default.
- W2364306561 hasIssue "3" @default.
- W2364306561 hasLocation W23643065611 @default.
- W2364306561 hasLocation W23643065612 @default.
- W2364306561 hasOpenAccess W2364306561 @default.
- W2364306561 hasPrimaryLocation W23643065611 @default.
- W2364306561 hasRelatedWork W1986804947 @default.
- W2364306561 hasRelatedWork W1987724165 @default.
- W2364306561 hasRelatedWork W1988438008 @default.
- W2364306561 hasRelatedWork W1996272233 @default.
- W2364306561 hasRelatedWork W2019685157 @default.
- W2364306561 hasRelatedWork W2019711527 @default.
- W2364306561 hasRelatedWork W2031505863 @default.
- W2364306561 hasRelatedWork W2048106517 @default.
- W2364306561 hasRelatedWork W2050835782 @default.
- W2364306561 hasRelatedWork W2056508438 @default.
- W2364306561 hasRelatedWork W2104978342 @default.
- W2364306561 hasRelatedWork W2128634625 @default.
- W2364306561 hasRelatedWork W2135875884 @default.
- W2364306561 hasRelatedWork W2158398784 @default.
- W2364306561 hasRelatedWork W2165788941 @default.
- W2364306561 hasRelatedWork W2171656551 @default.
- W2364306561 hasRelatedWork W2354481371 @default.
- W2364306561 hasRelatedWork W2358562921 @default.
- W2364306561 hasRelatedWork W2361740559 @default.
- W2364306561 hasRelatedWork W2400099095 @default.
- W2364306561 hasVolume "37" @default.
- W2364306561 isParatext "false" @default.
- W2364306561 isRetracted "false" @default.
- W2364306561 magId "2364306561" @default.
- W2364306561 workType "article" @default.