Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364341015> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2364341015 abstract "Objective To analyze different platelet activation indexes in hyperlipemia rats,including maximum platelet agglutination rate(MPAR)induced by adenosine diphosphate(ADP)and arachidonic acid(AA),P-Selectin,thromboxane B2(TXB2),6-keto-prostaglandin F1a(6-k-PGF1a),TXB2/6-k-PGF1a(TP)ratio and the expression of CD62 on the surface of platelet,and to evaluate the correlation between different indexes.Methods Twenty-four Wistar rats were randomly divided into groups control and high-fat-diet.After eight weeks of intervention,MPAR induced by ADP and AA were detected,the concentrations of P-Selectin,TXB2,6-k-PGF1a were determined by euzymelinked immunosorbent assay,the expression of CD62 on platelet surface by flow cytometric(FCM) analysis.The database was established by Excel software and analyzed by SPSS 11.5 software.Results After high-fat intervention,there was significant difference in ADP-and AA-induced MPAR,P-Selectin,TXB 2,6-k-PGFla,TP ratio,platelet CD62P between high-fat-diet group(55 +14%,30 +8%,27.0 +2.8μg/L,54 +9μg/L,12.6 +2.8μg/L,3.25 +0.61,25.2 +5.3 %,respectively)and control(24 +5%,17 +3%,10.7 +1.7μg/L,14 +4μg/L,24.8 +4.6μg/L,0.54 +0.15,10.1 +1.3,respectively)(P0.001).The analysis results of different relevant indicators showed that the correlation coefficients of ADP-and AA-induced MPAR,P-Selectin,TXB 2,6-k-PGFla,TP ratio and platelet CD62 expression were 0.587,0.672,0.861,0.775,-0.777,0.830,respectively(P0.01).Conclusion Hyperlipemia spurs platelet to activation in rats.Except platelet CD62p,P-Selectin and TP ratio can reflect better the platelet activation." @default.
- W2364341015 created "2016-06-24" @default.
- W2364341015 creator A5058622349 @default.
- W2364341015 date "2009-01-01" @default.
- W2364341015 modified "2023-09-24" @default.
- W2364341015 title "Comparative Study of Different Platelet Activation Indexes in Hyperlipemia Rats" @default.
- W2364341015 hasPublicationYear "2009" @default.
- W2364341015 type Work @default.
- W2364341015 sameAs 2364341015 @default.
- W2364341015 citedByCount "0" @default.
- W2364341015 crossrefType "journal-article" @default.
- W2364341015 hasAuthorship W2364341015A5058622349 @default.
- W2364341015 hasConcept C126322002 @default.
- W2364341015 hasConcept C134018914 @default.
- W2364341015 hasConcept C181199279 @default.
- W2364341015 hasConcept C185592680 @default.
- W2364341015 hasConcept C2776785769 @default.
- W2364341015 hasConcept C2778078955 @default.
- W2364341015 hasConcept C2781080829 @default.
- W2364341015 hasConcept C3018697912 @default.
- W2364341015 hasConcept C55493867 @default.
- W2364341015 hasConcept C71924100 @default.
- W2364341015 hasConcept C89560881 @default.
- W2364341015 hasConceptScore W2364341015C126322002 @default.
- W2364341015 hasConceptScore W2364341015C134018914 @default.
- W2364341015 hasConceptScore W2364341015C181199279 @default.
- W2364341015 hasConceptScore W2364341015C185592680 @default.
- W2364341015 hasConceptScore W2364341015C2776785769 @default.
- W2364341015 hasConceptScore W2364341015C2778078955 @default.
- W2364341015 hasConceptScore W2364341015C2781080829 @default.
- W2364341015 hasConceptScore W2364341015C3018697912 @default.
- W2364341015 hasConceptScore W2364341015C55493867 @default.
- W2364341015 hasConceptScore W2364341015C71924100 @default.
- W2364341015 hasConceptScore W2364341015C89560881 @default.
- W2364341015 hasLocation W23643410151 @default.
- W2364341015 hasOpenAccess W2364341015 @default.
- W2364341015 hasPrimaryLocation W23643410151 @default.
- W2364341015 hasRelatedWork W1509003797 @default.
- W2364341015 hasRelatedWork W1579367035 @default.
- W2364341015 hasRelatedWork W1983273497 @default.
- W2364341015 hasRelatedWork W1993060310 @default.
- W2364341015 hasRelatedWork W2012568798 @default.
- W2364341015 hasRelatedWork W2043080073 @default.
- W2364341015 hasRelatedWork W2089766956 @default.
- W2364341015 hasRelatedWork W2125763600 @default.
- W2364341015 hasRelatedWork W2129884947 @default.
- W2364341015 hasRelatedWork W2159357111 @default.
- W2364341015 hasRelatedWork W2355528719 @default.
- W2364341015 hasRelatedWork W2358392972 @default.
- W2364341015 hasRelatedWork W2359497080 @default.
- W2364341015 hasRelatedWork W2360331077 @default.
- W2364341015 hasRelatedWork W2369228763 @default.
- W2364341015 hasRelatedWork W2369762242 @default.
- W2364341015 hasRelatedWork W2375839559 @default.
- W2364341015 hasRelatedWork W2380288398 @default.
- W2364341015 hasRelatedWork W2388606528 @default.
- W2364341015 hasRelatedWork W2402188131 @default.
- W2364341015 isParatext "false" @default.
- W2364341015 isRetracted "false" @default.
- W2364341015 magId "2364341015" @default.
- W2364341015 workType "article" @default.