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- W2364343022 abstract "Objective:To investigate the protective effect of EGb761 on hydrogen peroxide-induced oxidative stress injury in fibroblast.Methods:The primary rat dermis fibroblasts were isolated and cultured in vitro,which were treated with Ginkgo biloba extract in different concentration(20mg/L,50mg/L,100mg/L)in exponential phase of cell growth and then exposed to hydrogen peroxide.The cell viability was determined using MTT assay.Superoxide dismutase(SOD)activity and malonyldialdehyde(MDA)content were measured by spectro-scope respectively.Reactive oxygen species(ROS)and apoptotic were measured by flow cytometry.Results:The results showed that different concentrations EGb761 evidently improved H2O2-induced cell viability and SOD activity;decreased apoptotic ratio,MDA contents and ROS level with a dose-related manner.Conclusion:The results suggest that EGb761 can protect oxidative stress injury induced by hydrogen peroxide in fibroblast." @default.
- W2364343022 created "2016-06-24" @default.
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- W2364343022 date "2009-01-01" @default.
- W2364343022 modified "2023-09-28" @default.
- W2364343022 title "The Protective Effect of EGb761 on Hydrogen Peroxide-induced Oxidative Stress Injury in Fibroblast" @default.
- W2364343022 hasPublicationYear "2009" @default.
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