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- W2364350166 abstract "Objective:To assess the effects of different concentrations of AS101 on sleep-wake cycle in rats.Methods:The electroencephalogram and electromyogram were recorded to study the effect of AS101 on sleep-wake cycle.Results:In comparison with the rats injected with buffer solution of pH 7.4,low does of AS101 injected in light-onset increased NREM time from(276.28±35.73)min to(308.38±30.68)min and decreased wake time from(165.00±35.12)min to(134.36±24.47)min,while high does of AS101 injected in light-onset increase NREM time from(272.28±35.16)min to(302.98±28.11)min in rats,low does of AS101 injected in dark-onset did not affect the sleep-wake cycle of rats both at wake time and NREM time.Conclusion:AS101 may be effective to increase NREM of rats and adjust their sleep-wake cycle." @default.
- W2364350166 created "2016-06-24" @default.
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- W2364350166 date "2008-01-01" @default.
- W2364350166 modified "2023-09-28" @default.
- W2364350166 title "An effect of a new type of interleukin-10 antagonist AS101 on the sleep-wake cycle in rats" @default.
- W2364350166 hasPublicationYear "2008" @default.
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