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- W2364355073 abstract "Objective: To observe the lesions of spinal cord and tissues around it in rabbits by intrathecal injection of collagenase with different concentrations. Methods: Forty rabbits were divided into five groups (A,B,C,D and E). 0.3mL of diluent physiological saline and 24,50,100,250U collagenase were injected into subarachnoid, and then the effects of collagenase in the spinal cord were observed by morphologic features, spinal cord evoked potential(SCEP) and pathologic changes. Results: Many rabbits in the four groups (B,C,D,E) became paraplegic in the hind limbs within 4 hours, the others had some changes of SCEP. Except the 8 rabbits in the control group of diluent, all of the rabbits had some damage in the spinal cord according to the results of microscopic examination, the more doses of collagenase, the more severe damage. Conclusion: The rabbits subjected to severe damage in the spinal cord if the collagenases were injected into the intrathecally." @default.
- W2364355073 created "2016-06-24" @default.
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- W2364355073 date "2001-01-01" @default.
- W2364355073 modified "2023-09-28" @default.
- W2364355073 title "The Lesions in the Spinal Cord and Tissues around It in Rabbits by Intrathecal Injection of Collagenase" @default.
- W2364355073 hasPublicationYear "2001" @default.
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