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- W2364355339 abstract "Objective To investigate the protective effect of extract from Balanophora spicata Hayata on alcoholic fatty liver disease in rat,and elucidate the possible mechanism.Methods 40 adult SD rats were randomly divided into normal group fed with physiological saline,model group fed with alcohol,low and high dose of extract from Balanophora spicata Hayata groups fed with alcohol and extract from Balanophora spicata Hayata(1.5,3.0 g·kg-1·d-1).After 10 days,the serum alanine aminotransferase(ALT),aspartate aminotransferase(AST) and the contents of malondialdehyde(MDA),glutathione perloxldase(GSH-Px),superoxide dismutase(SOD) in liver homogenate were detected,and the histological changes in liver were evaluated.Results Compared with the model group,extract from Balanophora spicata Hayata significantly decreased the serum transaminase levels and the content of MDA,enhanced SOD and GSH-Px levels in liver homogenate.Histopathological observations were consistent with biochemical changes,suggesting marked protective effect of extract from Balanophora spicata Hayata on acute liver injury in rat.Conclusions Extract from Balanophora spicata Hayata has an obviously protective effect against liver injury induced by alcohol in rat." @default.
- W2364355339 created "2016-06-24" @default.
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- W2364355339 date "2012-01-01" @default.
- W2364355339 modified "2023-09-23" @default.
- W2364355339 title "Protective effect of extract from Balanophora spicata Hayata on liver injury induced by alcohol in rat" @default.
- W2364355339 hasPublicationYear "2012" @default.
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