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- W2364358086 abstract "Objective:To investigate the expres sion of CD44v6 and nm23H1 mRNA,and the clinical significance and correlativity i n primary lung carcinoma.Methods CSA hydridization method was applied to test th e expression of CD44v6 and nm23H1 mRNA of lung carcinoma in 65 cases,which were studied and analyzed with their clinicopathologe features and follow-up cases.Re sults:The positive expression of CD44v6 and nm23H1 mRNA in lung carcinoma was 66 .2% and 49.2% respectively.Overexpression of CD44v6 mRNA and low expression of n m23H1 mRNA were positively correlated with PTNM stages,Pathologic grades and lym ph node metastasis in lung carcinoma.The patients of that were poor prognosticat ed five-year surviral rate.The expression of CD44v6 mRNA Showed paradoxical rela tionship with that of nm23H1 mRNA.Conclusions:The expression between CD44v6 and nm23H1 mRNA showed coordination of ngative correlation,which may serve as an imp ortant biological indicator of metastasis and prognosis of lung carcinoma." @default.
- W2364358086 created "2016-06-24" @default.
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- W2364358086 date "2002-01-01" @default.
- W2364358086 modified "2023-09-26" @default.
- W2364358086 title "Expression of CD44v6 and nm23H1 mRNA and their clinical significance in Human Iung Carcinoma" @default.
- W2364358086 hasPublicationYear "2002" @default.
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