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- W2364364306 abstract "Objective To discuss the diagnosis and the curative effect of repeat transsphenoidal surgery for recurrence of adrenocorticotropic hormone secreting pituitary adenomas. Methods 352 cases of pituitary adenomas were operated via transsphenoidal approach, and the serum cortisol level decreased to normal after the operation. Then the serum and urinary free cortisol (UFC) increased in 12 cases of patients and recurrence of pituitary adenomas of 9 patients were showed in CT or MRI. Repeat transsphenoidal surgery was performed on all 12 patients. Results The patients were followed up for 1-12 years. Clinic symptoms disappeared and UFC was normal or below normal in 7 patients. Pituitary irradiation and adrenalectomy were taken on 3 patients in whom UFC were still high after re-operation, and only adrenalectomy without pituitary irradiation was done in other 2 patients with high secretion of cortisol. Conclusion Repeat transsphenoidal surgery should be preferred for recurrence of adrenocorticotropic hormone secreting pituitary adenomas. Pituitary irradiation and adrenalectomy are assistant treatment for patients who still have high secretion of cortisol after repeat trannsphenoidal surgery." @default.
- W2364364306 created "2016-06-24" @default.
- W2364364306 creator A5062599033 @default.
- W2364364306 date "2004-01-01" @default.
- W2364364306 modified "2023-09-26" @default.
- W2364364306 title "Diagnosis and repeat transsphenoidal surgery for recurrence of adrenocorticotropic hormone secreting pituitary adenomas" @default.
- W2364364306 hasPublicationYear "2004" @default.
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