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- W2364367886 abstract "Objective To establish a nude mice transplantation tumor model with human invasive bladder cancer, study the expression level of vascular endothelial growth factor (VEGF) on the inocuated human invasive bladder cancer and explore the potential application of anti VEGF antibody to inhibit angiogenesis. Methods A nude mice model with human bladder cancer was established by subcutaneously inoculating T24 cells. The VEGF expression level in T24 cells and transplantation tumor tissue was measured by immunohistochemical method. Results The VEGF expression of T24 cell and T24 tumor xenograft was strongly positive in cytoplasm and the successful rate of the tumor transplantation was 94.4%. Conclusion VEGF induced angiogenesis is an important route of angiogenesis in human invasive bladder cancer tissue and found a base for the treatment and diagnosis of bladder cancer using anti VEGF antibody." @default.
- W2364367886 created "2016-06-24" @default.
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- W2364367886 date "2000-01-01" @default.
- W2364367886 modified "2023-09-25" @default.
- W2364367886 title "Establishment of a Nude mice transplantation tumor model with human invasive bladder cancer and the VEGF expression on inocuated tumor" @default.
- W2364367886 hasPublicationYear "2000" @default.
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