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- W2364385686 abstract "Objective To investigate the effects of PDGF-BB and ATRA on the differentiation of BM-MSCs into glomerular mesangial-like cells in vitro.Methods BM-MSCs were cultured using PDGF-BB and ATRA,and immunocytochemistry and Real-time RT-PCR were used to detect the specific proteins and genes.Results The results showed that the add of PDGF-BB and ATRA in induced medium resulted in MSCs differentiation into mesangial lineage,as indicated by a remarkable alteration in morphology,the up-regulation of specific cytoskeletal proteins and genes.Conclusion PDGF-BB and ATRA are required to induce mesangial differentiation of BM-MSCs." @default.
- W2364385686 created "2016-06-24" @default.
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- W2364385686 date "2011-01-01" @default.
- W2364385686 modified "2023-09-28" @default.
- W2364385686 title "In vitro effects of platelet-derived growth factor-BB and all-trans retinoic acid on differentiation of human bone marrow-derived mesenchymal stem cells into glomerular mesangial-like cells" @default.
- W2364385686 hasPublicationYear "2011" @default.
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