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- W2364388058 abstract "Objective To explore the protective effect of raffinose-low potassium dextran(R-LPD) solution on isolated donor lung in different periods of time.Methods Forty eight SD rats were randomly divided into 2 groups of A(LPD) and B(R-LPD) with 24 rats each.The two groups were then respectively allocated into 4 subgroups according to different preservative periods of 4,8,12 and 24 h after flusion.Wet/dry weight ratio(W/D),malondialdehyde(MDA),myeloperoxidase(MPO) and superoxide dismutase(SOD) were measured and pulmonary structure was observed by HE staining.Results In group A,W/D,MDA,MPO and SOD were higher after 24 h preservation than those after 12 h preservation(P0.01).In group B,MDA,MPO and SOD were higher after 24 h preservation than those after 12 h preservation(P0.01).After 12 h preservation,SOD was higher in group B than that in group A(P0.05).After 24 h preservation,W/D,MDA and MPO were lower,but SOD was higher,in group B than those in group A(P0.05 or P0.01).After 24 h preservation,clear tissue architecture and slight inflammatory reaction were observed in group B,while destructive pulmonary structure,alveolar interstitial edema and irreversible inflamatory damage were markedly seen in group A.Conclusion Untill isolated lung was preserved for 24 h,the protective effect of R-LPD solution is better than that of LPD solution." @default.
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- W2364388058 date "2012-01-01" @default.
- W2364388058 modified "2023-09-24" @default.
- W2364388058 title "Protective effect of raffinose-low potassium dextran solution on isolated lung in rats" @default.
- W2364388058 hasPublicationYear "2012" @default.
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