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- W2364392395 abstract "AIM:To study the effects of Liu wei di huang pills(LWDH)on the vascular endothelial function in patients with type 2diabetes mellitus(T2DM).METHODS:Sixty patients with T2DM were randomized into LWDH group(n=30)and routine treatment group(n= 30).Meanwhile,10healthy subjects served as the normal control group.On the basis of routine western medicine,patients in LWDH group were treated with LWDH,with a treatment course of 12 weeks.The levels of nitric oxide(NO),endothelin-1(ET-1),super-oxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were detected and the level of flow mediated vasodilatation(FMD)was assessed by Doppler ultrasound before and after 12 week treatment in all subjects. RESULTS:Before treatment the level of the ET-1in LWDH group and routine treatment group was significantly higher than those of control group(P0.01). However,the levels of the NO,SOD,GSHPX,and FMD were significantly lower than that in control group(P0.01).As compared with those before treatment,those indexes after treatment were obviously improved in LWDH group and routine treatment group(P0.05). Furthermore,the improvement effect in LWDH group was more obvious than that in routine treatment group(P 0.05).CONCLUSION: LWDH pills can ameliorate the vascular endothelial function inT2DM on the basis of routine treatment." @default.
- W2364392395 created "2016-06-24" @default.
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- W2364392395 date "2013-01-01" @default.
- W2364392395 modified "2023-09-27" @default.
- W2364392395 title "Effects of Liu wei di huang pills on the vascular endothelial function in type 2 diabetes mellitus" @default.
- W2364392395 hasPublicationYear "2013" @default.
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