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- W2364394995 abstract "Objective To investigate the relationship between o xidative stress and renal anemia. Methods Sixty-eight chronic renal failure patients with the exce ption of diabetic nephropathy were enrolled. All patients had not suffered from disease of infection in the periods of experiment and had not accepted the formal treatm ent.Based on the level of hemoglobin (HB), they were divided into 2 groups: were 33 patients with HB9g/dl in group 1,including 18 male and 15 female,age ranged from 38 to71 and 35 patients with HB≤9g/dl in group 2,16 male and 19 female,ag e ranged from 21 to 71. lipid peroxidation (LPO),superoxide dismutase (SOD),seru m cholesterol(CHO), triglyceride (TG),albumin,creatinine and urea nitragen were measured. The Lpoand SOD of group 2 patients were detected again after being tre ated with erythropoiesis iron, vitc and vit E.results LPO concentration in group 1 patients was significantly lower than that of group 2 patients (P0.05),the SOD, serum alb umin and CHO were higher than those of group 2 patients(P0.05). The level of TG and PLT in group 1 were higher than group 2 (P0.05). LPO and SOD levels in group 2 patients were significantly different befo re and after treatment. HB was negatively correlated with LPO and positively or related with SOD. Conclusion Erythrocytes contains highly effective free radical s cavengers. When renal anemia present, Decreased SOD can reduce increased oxidati ve stress and LPO products; Oxidative stress was improved by correction of the r enal anemia and supplement of antioxidant." @default.
- W2364394995 created "2016-06-24" @default.
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- W2364394995 date "2005-01-01" @default.
- W2364394995 modified "2023-09-26" @default.
- W2364394995 title "The relationship between oxidative stress and renal anemia" @default.
- W2364394995 hasPublicationYear "2005" @default.
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