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- W2364398433 abstract "Objective:To study the level changes of serum C reactive protein(CRP) and vascular endothelial growth factor(VEGF),and the clinical significance of detection of CRP and VEGF.Methods:Serum IL-6 and VEGF were determined by ELISA assay in 41 patients with CNG and 35 normal people.The radio immunoassay was applied to detect serum TNF-α,and immunoturbidimetry to detect serum CRP and urine Alb.Results:① Serum IL-6,TNF-α and CRP in patients with CNG were higher than control group(P0.01),and Serum IL-6,TNF-α and CRP in patients after treatment were significantly lower than before treatment(P0.01).There were positive correlation between serum IL-6,TNF-α and CRP levels(P0.01).②After treatment,the serum CRP and urine Alb significantly decreased(P0.01 or P0.05),but still higher than control group(P0.01).The serum VEGF levels were positively correlated with urine Alb(P0.01).Conclusion:IL-6,TNF-α,CRP may be involved in chronic inflammatory process in CNG,and VEGF has close relation-ship with proteinuria.Detection of serum CRP and VEGF before and after treatment plays important role in understanding the pathoge-netic condition and observing efficacy of patients with CNG." @default.
- W2364398433 created "2016-06-24" @default.
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- W2364398433 date "2011-01-01" @default.
- W2364398433 modified "2023-09-26" @default.
- W2364398433 title "Clinical significance of detection of serum CRP and VEGF levels before and after treatment in patients with chronic glomerular nephritis" @default.
- W2364398433 hasPublicationYear "2011" @default.
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