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- W2364404571 abstract "Objective To evaluate the value of Hydrogen 1 Magnetic Resonance Spectroscopy(1H-MRS) in lateralization of temporal lobe epilepsy (TLE) in adolescent. Materials and Methods Twenty seven TLE patients with negative conventional Magnetic Resonance Imaging(MRI) and ten healthy adolescent controls were studied by 1H-MRS using single voxel short echo time with the point resolved spatial selection (PRESS) protocol. 24-hour Electroencephalogram(EEG) was also used as the standard for epileptogenic focus localization. The ratio of NAA/(Cho+Cr),Glx and mI in lateralizing focus were analysed. Results Successful 1H-MRS were achieved in 22 patients (22/27) and 10 healthy controls with stable baselines and good signal/noise ratio. Comparing to the mean values of ten healthy controls, 22 patients showed abnormal NAA/(Cho+Cr) ratios at the hippocampal area. 15 cases had correct lateralization of focus in accordance with EEG(15/22). Conclusion Single voxel short echo 1H-MRS with PRESS protocol are helpful in finding abnormality in lateralization of temporal epilepsy with negative MRI findings." @default.
- W2364404571 created "2016-06-24" @default.
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- W2364404571 date "2008-01-01" @default.
- W2364404571 modified "2023-09-28" @default.
- W2364404571 title "Short Echo ~1H-MRS in Adolescent Temporal Lobe Epilepsy with Negative MRI Findings" @default.
- W2364404571 hasPublicationYear "2008" @default.
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