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- W2364408751 abstract "Objective and Methods To investigate the effect of intracerebroventricular infusion of artificial sodium rich cerebrospinal fluid on the release of endogenous digitalis like factor (EDLF) and renal Na +·K + ATPase activity. Results In anesthetized rats, intracerebroventricular infusion of artificial sodium rich cerebrospinal fluid inceased the level of serum EDLF and decreased renocortical Na +·K + ATPase activity(P0.01).Similar injection of hypertonic sucrose cerebrospinal fluid did not induce the increase of serum EDLF level and the decrease of renal Na +·K + ATPase activity. A significant correlation was observed between serum EDLF level and renocortical Na +·K + ATPase activity in rats(r= 0.746,P0.001). Conclusions These results indicats that the high sodium stimulation in cerebroventricle may induce the elevation of serum EDLF levels and the inhibiton of renal Na +·K + ATPase activity which is involed in the elevation of serum EDLF levels." @default.
- W2364408751 created "2016-06-24" @default.
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- W2364408751 date "2001-01-01" @default.
- W2364408751 modified "2023-09-25" @default.
- W2364408751 title "Effect of intracerebroventricular infusion of artificial sodium rich cerebrospinal fluid on endogenous digitalis like factor release and renal Na~+·K~+-ATPase activity in anesthetized rats" @default.
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