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- W2364430060 abstract "Objective:To investigate the relationship between oxygen free radical(OFR) and disease status,HBV DNAloads in patients with hepatitis B, Methods: According to their disease status,103 patients with hepatitis B were divided into HBV carrier(XD)( n =20) .acute hepatitis( AH) ( n =20) .chronic acute hepatitis(CAH)( n = 40)and liver cirrhosis(LC) (n = 23)groups. Another 20 healthy people were set as control group, In CAH group, 21 patients were given an anti-virus treatment for 6 months,and others were given an ordinary treatment. Before and after treatment,the levels of HBV DNA.superoxide dismutase(SOD) and MDA were measured in all of the patients and healthy people. Results: Compared with the control group, the levels of SOD and MDA in hepatitis B groups changed more significantly than in the control group(P 0.05) . In CAH group,HBV DNA loads reduced apparently after the anti-virus treatment, along with SOD being up and MDA being down. Conclusion: The metabolism of OFR is obviously abnormal in the patients with hepatitis B. Its level is significantly correlative with disease status and HBV DNA loads." @default.
- W2364430060 created "2016-06-24" @default.
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- W2364430060 date "2002-01-01" @default.
- W2364430060 modified "2023-10-18" @default.
- W2364430060 title "Relationship between Oxygen Free Radical and Disease Status, HBV DNA Load in Patients with Hepatitis B" @default.
- W2364430060 hasPublicationYear "2002" @default.
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