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- W2364430945 abstract "Objective The incidence of invasive pulmonary aspergillosis increases and the mortality rate is high,but the mechanism is unknown.The aim of this study is to investigate the role of E-cadherin in the process of Aspergillus fumigatus invasion of alveolar epithelial cells,A549 cell lines with high and low expression of E-cadherin were established.Methods Human E-cadherin gene cDNA and siRNA were cloned into the vector,and packaged into A549 cells by gene transfection technology.Results A549 strain with stably high and low expression of E-cadherin was proven by PCR and Western blot.Conclusion A549 cell lines with high and low expression of E-cadherin have been constructed successfully." @default.
- W2364430945 created "2016-06-24" @default.
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- W2364430945 date "2013-01-01" @default.
- W2364430945 modified "2023-09-24" @default.
- W2364430945 title "Construction of A549 line with low E-cadherin expression and high E-cadherin expression" @default.
- W2364430945 hasPublicationYear "2013" @default.
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