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- W2364431782 abstract "Objective: To investigate the effects of different colloid priming solutions (including human albumin, gelofusion,and 6% hydroxyethyl starch) on coagulation in the patients when undergoing cardiopulmonary bypass (CPB) operation.Methods: 36 patients undergoing open heart surgery with CPB were randomly divided into three groups (12 of each): human albumin group(A), gelofusion group (G), and 6% hydroxyethyl starch group (H). The venous blood samples were collected before anesthesia (T0), in 20 minutes of CPB (T1), at the end of CPB (T2), in 6 hours (T3) and 24 hours (T3) after the operation. Partial coagulation parameters (APTT,PT,FIB,FDP,D D,PLT) of the three groups were measured and compared with each other. Results: 1) Fibrinogen concentrations (FIB) of group A and group G at T1 and T2 were lower than those at T0 ( P 0 01). FIB of group G at T3 was still lower than that of T0 ( P 0 05). The prothrombin time (PT) in all groups at T3 were longer than those at T0 ( P 0 01). The activated partial thromboplastin time (APTT) of group H at T3 was longer than that at T0 ( P 0 01). The FIB of group A and group G at T4 were higher than that at T0 ( P 0 01); 2) PT of group H was longer than those of group A and group G at T3 ( P 0 05), The APTT of group H was longer than that of group A ( P 0 05) , FIB of group A and group G were higher than that of group H at T4 ( P 0 05). Conclusions: The coagulation function recovers faster using human albumin or gelofusion as priming solution than using 6% hydroxyethyl starch during CPB and the body stays in relatively high coagulation condition in the next day of the operation." @default.
- W2364431782 created "2016-06-24" @default.
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- W2364431782 date "2004-01-01" @default.
- W2364431782 modified "2023-09-25" @default.
- W2364431782 title "The Effects of Three Plasma Expanders as Priming Solution on Coagulation in Cardiopulmonary Bypass" @default.
- W2364431782 hasPublicationYear "2004" @default.
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