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- W2364432852 abstract "Objective To analyze the clinical value of Mycobacterium tuberculosis IFN-γ release assay(TB-IGRA) in diagnosis of tuberculosis. Methods The serum specimens of 249 patients with tuberculosis and 140 healthy people were detected by Mycobacterium tuberculosis-IFN-γ release assay with Wantai quantitative diagnostic kit(WT-IGRA,Beijing Wantai Biological Pharmacy Corporation Ltd.) and QuantiFERON-TB GOLD in tube(QFT-GIT,Cellestis Limited,Australia),respectively.The results of TB-IGRA with WT-IGRA and QFT-GIT were compared with BCG-PPD skin test,Sputum smear and mycobacterial culture. Results Among 249 patients with tuberculosis,the positive rate of TB-IGRA with WT-IGRA and QFT-GIT were 76.3%(190/249)and 67.1%(167/249),respectively,and the specificity with two methods were all 83.3%(100/120).There were no statistical significant differences on positive rates of TB-IGRA and QFT-GIT between smear-positive patients and smear-negative patients which were 74.1%(43/58),76.1%(83/109)with WT-IGRA(χ2=0.082,P0.05) and 67.2%(39/58),65.1%(71/109)with QFT-GIT(χ2=0.075,P0.05).The coincidence rate of the two kits is 84.3%. Conclusion TB-IGRA has certain diagnostic value in tuberculosis." @default.
- W2364432852 created "2016-06-24" @default.
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- W2364432852 date "2011-01-01" @default.
- W2364432852 modified "2023-09-28" @default.
- W2364432852 title "Diagnostic value of quantitative diagnostic kit for Mycobacterium tuberculosis-IFN-γ release assay" @default.
- W2364432852 hasPublicationYear "2011" @default.
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