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- W2364447672 abstract "Objective To observe whether hind limb ischemia/reperfusion induces the haem oxygenase 1 (HO-1) expression in rat heart. Methods The urethane-anesthetized rats were undergone with hind limb ischemia/reperfusion. The contents of malondialdehyde (MDA) and activity of superoxide dismutase (SOD) in heart were detected. The expressions of HO-1 mRNA and protein in myocardium were measured by Northern blotting and Western blotting respectively.Results During limb ischemia/reperfusion, the content of MDA was increased and the activity of SOD was decreased in heart. The simple limb ischemia didn't induce the expressions of HO-1 mRNA and protein, but the levels of HO-1 mRNA and protein in the myocardium were increased by limb ischemia/reperfusion. Conclusion Limb ischemia/reperfusion could not only increase the content of MDA and decrease the activity of SOD in heart, but also upregulate the expression of HO-1 in heart." @default.
- W2364447672 created "2016-06-24" @default.
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- W2364447672 date "2001-01-01" @default.
- W2364447672 modified "2023-09-25" @default.
- W2364447672 title "Limb ischemia/reperfusion induces haem oxygenase 1 expression in rat heart" @default.
- W2364447672 hasPublicationYear "2001" @default.
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