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- W2364448972 abstract "Objective:To test scotopic sensitivity and investigate whether there is rod system dysfunction in the central retina in early stage of age-related macular degeneration (AMD). Methods:Scotopic (450nm) and photopic (white) sensitivity were measured at 81 loci in central 25° of retina in 25 patients with early stage AMD,and the results were compared with older adult normal controls. Results:Mean scotopic sensitivity of AMD patients was significantly lower than that of normal subjects.The ratio of reduced scotopic sensitivity was higher than that of photopic sensitivity in patients with the losses of scotopic and photopic sensitivities.The loss of scotopic sensitivity decreased with the increasing of eccentricity,and the greatest deficit was from 2 5° to 5 0°. Conclusions:Scotopic sensitivity decreased and parafoveal rod cells had a selective vulnerability in early stage of AMD patients.Scotopic sensitivity testing in macula may be a useful tool to measure the fundus pathology and to diagnose the AMD." @default.
- W2364448972 created "2016-06-24" @default.
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- W2364448972 date "2003-01-01" @default.
- W2364448972 modified "2023-09-23" @default.
- W2364448972 title "Scotopic sensitivity of central 25° in early age-related macular degeneration" @default.
- W2364448972 hasPublicationYear "2003" @default.
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