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- W2364451085 abstract "Objective:To examine the concentration of 10 protein markers in patients with acute coronary syndrome(ACS)with extra protein chips and to explore its clinical significance. Methods:Combination detection of serum and plasma levels of 10 cytokines was performed in a prospective study of 104 pa- tients with documented ACS and 50 controls. Results:The levels of serum MMP-9,sCD4OL,sVCAM-1,CRP,IL-6,H-FABP,cTnI,and plasma ET-1,Npro-BNP and IL-8 in acute myocardial infarction(AMI),unstable angina pectoris(UAP)patients were much higher than those of the controls (P＜0.01).The levels of serum cTnI and H-FABP in the AMI patients were much higher than those of UAP patients(P＜0.01).There was a close relationship both between the level of CRP and that of IL-6(r=0.961,P＜0.01)and between the level of sCD40L and that of sVCAM-1(r=0.644,P＜0.01).There was no relationship between the level of sCD40L and that of MMP-9(r=0.158,P＞0.05).The comparison of the two methods showed that there was no significant difference between serum H-FABP and sCD40L in patients with ACS. Conclusions:It showed that the levels of 10 protein markers in ASC patients are abnormal.The results can be used as detec- tion markers of ACS at a molecular level." @default.
- W2364451085 created "2016-06-24" @default.
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- W2364451085 date "2006-01-01" @default.
- W2364451085 modified "2023-09-23" @default.
- W2364451085 title "Conabination Detection of Protein Markers in Patients With Acute Coronary Syndrome" @default.
- W2364451085 hasPublicationYear "2006" @default.
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