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- W2364451712 abstract "The poly(N-isopropylacrylamide) (PNIPA) and poly(N-isopropylacrylamide-co-acrylic acid) (PNIPA-co-PAAc) hydrogels with thermosensitive and pH-sensitive properties were synthesized by free radical polymerization. The effects of the amount of initiator, cross-linker, and the ratios of NIPA to AAc on the properties of hydrogels were studied. It was found that all hydrogels exhibited reversible phase-transition phenomenon at the lower critical solution temperature (LCST). Furthermore, their LCSTs increased successively depending on the amount of AAc in feed and the swelling properties of them at high pH were much better than low one. In vitro of drug (Aspirilin) was taken under a condition of gastrointestinal fluid and the body temperature (37 ℃). It was identified that hydrogel particles as drug matrixes could deliver much longer and more validly." @default.
- W2364451712 created "2016-06-24" @default.
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- W2364451712 date "2002-01-01" @default.
- W2364451712 modified "2023-09-25" @default.
- W2364451712 title "Studies on Synthesis of Thermosensitive Hydrogels and Vitro Release" @default.
- W2364451712 hasPublicationYear "2002" @default.
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