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- W2364453203 abstract "Objective To investigate the expression and significance of VE-cadherin in intravenous serum and umbilical cord blood of patients with hypertensive disorders in pregnancy (pregnancy-induced hypertension syndrome,PIH).Methods Contents of VE-cadherin in intravenous serum and umbilical cord blood from 90 patients with hypertensive disorders in pregnancy (which were divided into gestational hypertension,mild and severe preeclampsia groups each including 30 patients) were detected by enzyme-linked immunosorbent assay(ELISA) respectively.Contents of high-sensitive C-reactive protein(hs-CRP) of above were detected by immunoturbidimetry.30 normal pregnant women were taken as control group.Results VE-cadherin expressed in both patients and controls.Serum contents in patients and controls had significant difference by comparison (t=7.31,9.82,10.04,all P0.05).Moreover,there were differences among the contents of three groups(t=7.23,8.95,7.68,all P0.05).hs-CRP expressed in both patients and controls.Serum contents in patients and controls had significant difference by comparison (t=8.64,11.53,15.26,all P0.05).Moreover,there were differences among the contents of three groups(t=6.53,8.21,8.02,all P0.05).Contents of VE-cadherin and hs-CRP of patients with hypertensive disorders in pregnancy showed a positive correlation (r=0.60,P0.01).There were no significant differences in contents of VE-cadherin and hs-CRP in umbilical cord blood of patients with hypertensive disorders inpregnancy in three groups(P0.05).Conclusions The high expression of VE-cadherin and hs-CRP in patients with hypertensive disorders in pregnancy indicates the injury of vascular endothelium cells and VE-cadherin and hs-CRP play a role in the process of injury." @default.
- W2364453203 created "2016-06-24" @default.
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- W2364453203 date "2009-01-01" @default.
- W2364453203 modified "2023-09-23" @default.
- W2364453203 title "Expression of VE-cadherin in peripheral blood and umbilical cord blood of patients with hypertensive disorders in pregnancy" @default.
- W2364453203 hasPublicationYear "2009" @default.
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