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- W2364459629 abstract "Objective To explore the value of VEGF,TPS,CA125 serum levels in analyse prognostic criteria for non-Hodgkin lymophoma(NHL) and its correlation with stage.Methods The clinical datas of 30 patients were chosen as research objects.They were all first diagnosed patients,who had received no less than two phases of chemotherapy in Fujian Provincial Hospital from february 2009 to february 2011.Among them there were 18 patients in the effective group(CR+PR),and 12 patients in the ineffective group(SD+PD).Meanwhile 20 healthy volunteers and 10 patiens with benign lesions of lymph node were selected as control groups.Enzyme-linked immunosorbent assay was used to detect the serum levels of VEFG,TPS,CA125 in the three groups before the chemotherapy and after two periods of chemotherapies.Results The serum levels of VEFG,TPS,CA125 were significantly higher in NHL group,compared with other two groups(P0.05).But the serum levels of those were not significantly differente between healthy group and benign lesions of lymph node group(P0.05).In the NHL group,the serum levels of VEGF,TPS were higher in phase Ⅲ/Ⅳ,compared with phase Ⅰ/Ⅱ(P0.05),and the level of CA125 showed no correlation with periodization.In the effective group,the serum levels of VEGF,TPS,CA125 were significantly lower after two periods of chemotherapies,compared with prior to chemotherapy(P0.05);but the serum levels of those were not significantly differente between two time points in the ineffective group(P0.05).Conclusion The serum levels of VEFG,TPS,CA125 were significantly higher in NHL group,and even higher in the more advanced patients.The serum levels were significantly lower after effective chemotherapy." @default.
- W2364459629 created "2016-06-24" @default.
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- W2364459629 date "2012-01-01" @default.
- W2364459629 modified "2023-09-23" @default.
- W2364459629 title "The Serum Levels of VEGF,TPS and CA125 in NHL Patients and its Clinical Significance" @default.
- W2364459629 hasPublicationYear "2012" @default.
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