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- W2364464552 abstract "Objective: To detect the expression of high sensitivity C-reactive protein(hs-CRP) in serum and CX3C-chemokine receptor 1(CX3CR1) in peripheral blood mononuclear cells(PBMC) in patients with acute progressive cerebral infarction(APCI),and to study its clinical significance.Methods: Collect 91 patients of acute cerebral infarction lasting 24 h divided into two groups,one was progressive group with 28 patients with APCI and another was stable group with 63 patients with acute cerebral infarction.The hs-CRP in serum and CX3CR1 in PBMC were detected by immunoturbidimetry and flow cytometry at admission,7th,14th,30th day.Results: The expression of hs-CRP in serum and CX3CR1 in PBMC in patients with APCI was higher than the ones with ACI at admission,7th,14th,30th day.The differences were statistically significant(P0.05).The expression of hs-CRP and CX3CR1 increased to peak on 7th day,then on a declining curve.Conclusion: Inflammation in the whole process of acute cerebral infarction occurrence and development.The over expression of CX3CR1 in PBMC may be one of the molecular biology mechanism in the occurrence and development of APCI.To detect the expression of hs-CRP in serum and CX3CR1 in PBMC in patients with ACI may be helpful with the early diagnosis and protection of APCI." @default.
- W2364464552 created "2016-06-24" @default.
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- W2364464552 date "2011-01-01" @default.
- W2364464552 modified "2023-09-28" @default.
- W2364464552 title "Expression and significance of hs-CRP in serum and CX3CR1 in PBMC in patients with acute progressive cerebral infarction" @default.
- W2364464552 hasPublicationYear "2011" @default.
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