Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364465902> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2364465902 abstract "Objective:To investigate the relationship between polymorphism of reduced folate carrier gene RFC1-G 80A G 80A and the susceptibility of gastric cancer in Chinese Han population in the area of East China.Methods:A case-control study was performed in Yixing city of East China.Two hundred and sixty one patients with gastric adenocarcinoma confirmed by histological examination and 295 age-and sex frequency-matched cancer-free control participated in this study.Genotypes of RFC1-G 80A gene were determined by the polymerase chain reaction-restriction fragment length polymorphism method.The relationship between different genotype and risk of gastric cancer was compared and the influence of smoking and wine drinking were discussed.Results:Logistic regression analysis revealed that compared with wild 80GG genotype individuals carrying 80AA variant genotype had a significantly increased risk(1.79 fold) of gastric cancer(risk increase: 1.79 fold;adjusted OR=2.79;95%CI: 1.77-4.39).Furthermore,individuals with 80AA genotype had a 2.59-fold risk of gastric cancer(adjusted OR=2.59;95%CI: 1.77-3.80) compared with 80GG/GA genotypes.In addition,the stratification analysis showed that the association was more significant in subgroups of relatively older(≥60 years)(adjusted OR=2.96;95%CI: 1.63-5.37),females(adjusted OR=(8.28);95%CI: 2.95-23.26),non-smokers(adjusted OR=3.68;95%CI: 1.94-6.98),and non-drinkers (adjusted OR=3.08,95%CI: 1.76-5.41).Conclusion:These findings support the hypothesis that the polymorphism of RFC1-G 80A gene may be associated with the susceptibility of gastric cancer in Chinese Han population.Further functional studies in large sample population are needed to confirm our findings." @default.
- W2364465902 created "2016-06-24" @default.
- W2364465902 creator A5002274155 @default.
- W2364465902 creator A5039450674 @default.
- W2364465902 date "2006-01-01" @default.
- W2364465902 modified "2023-09-25" @default.
- W2364465902 title "Molecular epidemiological study on the relationship between polymorphism of reduced folate carrier gene RFC1-G80A and susceptibility of gastric cancer" @default.
- W2364465902 hasPublicationYear "2006" @default.
- W2364465902 type Work @default.
- W2364465902 sameAs 2364465902 @default.
- W2364465902 citedByCount "0" @default.
- W2364465902 crossrefType "journal-article" @default.
- W2364465902 hasAuthorship W2364465902A5002274155 @default.
- W2364465902 hasAuthorship W2364465902A5039450674 @default.
- W2364465902 hasConcept C104317684 @default.
- W2364465902 hasConcept C107130276 @default.
- W2364465902 hasConcept C121608353 @default.
- W2364465902 hasConcept C126322002 @default.
- W2364465902 hasConcept C135763542 @default.
- W2364465902 hasConcept C146304588 @default.
- W2364465902 hasConcept C151956035 @default.
- W2364465902 hasConcept C54355233 @default.
- W2364465902 hasConcept C71924100 @default.
- W2364465902 hasConcept C86803240 @default.
- W2364465902 hasConcept C90924648 @default.
- W2364465902 hasConceptScore W2364465902C104317684 @default.
- W2364465902 hasConceptScore W2364465902C107130276 @default.
- W2364465902 hasConceptScore W2364465902C121608353 @default.
- W2364465902 hasConceptScore W2364465902C126322002 @default.
- W2364465902 hasConceptScore W2364465902C135763542 @default.
- W2364465902 hasConceptScore W2364465902C146304588 @default.
- W2364465902 hasConceptScore W2364465902C151956035 @default.
- W2364465902 hasConceptScore W2364465902C54355233 @default.
- W2364465902 hasConceptScore W2364465902C71924100 @default.
- W2364465902 hasConceptScore W2364465902C86803240 @default.
- W2364465902 hasConceptScore W2364465902C90924648 @default.
- W2364465902 hasLocation W23644659021 @default.
- W2364465902 hasOpenAccess W2364465902 @default.
- W2364465902 hasPrimaryLocation W23644659021 @default.
- W2364465902 hasRelatedWork W1489977196 @default.
- W2364465902 hasRelatedWork W1761775793 @default.
- W2364465902 hasRelatedWork W1928664469 @default.
- W2364465902 hasRelatedWork W1980634339 @default.
- W2364465902 hasRelatedWork W1998517993 @default.
- W2364465902 hasRelatedWork W2017325389 @default.
- W2364465902 hasRelatedWork W2105755890 @default.
- W2364465902 hasRelatedWork W2129658496 @default.
- W2364465902 hasRelatedWork W2346730671 @default.
- W2364465902 hasRelatedWork W2352563612 @default.
- W2364465902 hasRelatedWork W2355206922 @default.
- W2364465902 hasRelatedWork W2355725065 @default.
- W2364465902 hasRelatedWork W2372011757 @default.
- W2364465902 hasRelatedWork W2387585686 @default.
- W2364465902 hasRelatedWork W2461828463 @default.
- W2364465902 hasRelatedWork W2464998802 @default.
- W2364465902 hasRelatedWork W2567011622 @default.
- W2364465902 hasRelatedWork W2980597511 @default.
- W2364465902 hasRelatedWork W3023742335 @default.
- W2364465902 hasRelatedWork W3150188641 @default.
- W2364465902 isParatext "false" @default.
- W2364465902 isRetracted "false" @default.
- W2364465902 magId "2364465902" @default.
- W2364465902 workType "article" @default.