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- W2364488372 abstract "Objective To investigate the change of free radicals metabolic state in gastrointestinal cancer patients and its role in the progress of gastrointestinal cancer.Methods The activity levels of plasma reactive oxygen species(ROS),superoxide dismutase(SOD) and glutathione peroxidase(GSH -PX) in 148 gastrointestinal cancer patients(cancer group) and 40 healthy check - up subjects(control group) were determinated by Fenton reaction method,xanthine oxidase method and dithiocarbamate method respectively.Results Plasma ROS activity(1197.844±489.640) U/ml in GIC increased significantly in comparison with the control group(507.706±17.525) U/ml(P0.05).Plasma SOD and GSH - PX activities (81.884±40.893)nmol/ml,(87.143±69.119)AU in GIC decreased significantly in comparison with the control group (101.166±18.350)nmol/ml,(438.933±138.201)AU(P0.05).Conclusion The metabolism of free radical is disturbed and the ability of anti - oxidation damage decreases significantly in patients with GIC,oxidation damage may have some relationship with the onset and development of GIC." @default.
- W2364488372 created "2016-06-24" @default.
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- W2364488372 date "2010-01-01" @default.
- W2364488372 modified "2023-09-26" @default.
- W2364488372 title "The determination of plasma ROS,SOD and GSH - PX activity in gastrointestinal cancer patients" @default.
- W2364488372 hasPublicationYear "2010" @default.
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