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- W2364490060 abstract "Aim: To detect the expressions of chemokine receptor-7(CCR7) and integration of glomerular epithelial membrane protein ( Podoplanin) in esophageal squamous cell carcinoma(ESCC) tissue. Methods: Immunohistochemical SP method was used to detect the expressions of CCR7 and Podoplanin in 40 cases of ESCC and their adjacent normal esophageal mucosal tissue,and the relationship of CCR7,lymphatic microvessel density (MLVD) and their clinicopathological characteristics was analyzed. Results: The positive expression rate of CCR7 and MLVD in ESCC tissue were higher than those in adjacent normal esophageal mucosa tissue (χ2=23. 310,P0.001; Z=5. 416,P0.001) ; the expressions of Podoplanin in positive ESCC group was higher than that in negative ESCC group of( t=3. 478,P0.001) . The expressions of CCR7 and Podoplanin were related with pathological stage and lymph node metastasis of ESCC (χ2=6. 114,P=0.013;χ2=4. 352,P=0.035; t=3.668,P0.001; t=4.888,P0.001) . Conclusion: The increased expressions of CCR7 and Podoplanin may promote the invasion and lymph node metastasis of ESCC." @default.
- W2364490060 created "2016-06-24" @default.
- W2364490060 creator A5056566121 @default.
- W2364490060 date "2013-01-01" @default.
- W2364490060 modified "2023-09-24" @default.
- W2364490060 title "Expressions of CCR7 and Podoplanin protein in esophageal squamous cell carcinoma tissue" @default.
- W2364490060 hasPublicationYear "2013" @default.
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