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- W2364494524 abstract "Objective To establish the scientific quality standards of blood with the removal of leukocytes by investigating the best preparing technique and process.Methods Collecting blood were filtrated respectively with leukocyte filter by three methods: connection of sterile catheter,direct filtration and filtration after storage.The differences of these methods were contrasted by analyzing the index about blood quality after filtration.Results By the two methods: connection of sterile catheter and direct filtration,all blood components were prepared in 6 hours after collection to ensure quality of thrombocyte and fresh frozen plasma.Compared with the above-mentioned,the methods of filtration after storage and direct filtration(the storage time of blood are more than 96 hours) have some limitations: the fragility of erythrocyte membrane was increased,the level of IL-2 and IL-6 were elevated and the effect of removing leukocytes was decreased.Conclusion The method of filtrating collected blood in a short time to prepare blood with the removal of leukocytes is superior to the methods of connection of sterile catheter and filtration after storage.Especially the method of filtration after storage should be abandoned because the possibility of blood contamination was increased and the effect of removing leukocytes was reduced." @default.
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- W2364494524 date "2009-01-01" @default.
- W2364494524 modified "2023-09-23" @default.
- W2364494524 title "Establishment of the best technology to prepare blood with the removal of leukocytes and investigation of the quality standards" @default.
- W2364494524 hasPublicationYear "2009" @default.
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