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- W2364507662 abstract "Aim To synthesize novel β-elemene amino derivatives and to test their in vitro antitumor activities.Methods The target compounds were synthesized from β-elemene via chlorination and sequential amination.The in vitro anti-proliferative effects of the target compounds on HL-60,HeLa and SGC-7901cells were evaluated by SRB assay.Results and conclusion The structures of 12 novel compounds were characterized by IR,MS and 1H-NMR.Preliminary pharmacological results showed that most compounds possessed stronger antitumor activities than β-elemene." @default.
- W2364507662 created "2016-06-24" @default.
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- W2364507662 date "2009-01-01" @default.
- W2364507662 modified "2023-09-26" @default.
- W2364507662 title "Synthesis and anti-proliferative activity of β-elemene amino derivatives" @default.
- W2364507662 hasPublicationYear "2009" @default.
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