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- W2364522011 abstract "Objective To evaluate the efficacy and feasibility of clinical application of Sufentanil in lumbar epidural analgesia.Methods 54 patients were arranged for elective or limited upper abdominal major operations and they were randomly divided into 3 groups according to the epidural puncturing site of the high level,median level and low level.Postoperative analgesic effects,patient controlled epidural analgesia(PCEA) pump usage,drug consumption and side effects were observed within 48 h.Results There were no differences in VAS scores of the patients at resting or coughing between Group H and Group M(P0.05).At 2 and 4 h after operation,the resting VAS score in Group L was significantly higher than that in Group H and Group M(P 0.05).At 8,20,24,30 and 48 h after operation,there were no significant differences of resting VAS score among the 3 groups(P0.05).At 2,4 and 8 h after operation,the VAS score at coughing condition in Group L was significantly higher than that in Group H and Group M(P 0.05).Afterwards,there was no significant difference among the 3 groups(P0.05).Nausea was observed in 3 patients in each group within 48 h after operation and there were no significant differences(P0.05).Similarly,the incidences of itching among the 3 groups were not statistically significant(P0.05).No respiratory depression at any time point after operation in the 3 groups was observed.The difference in the cumulative consumption of Sufentanil at day-1 after operation between Group H,Group M and Group L was significant(P0.05).However,there were no significant differences in the consumption of Sufentanil in these 3 groups at the second day(P0.05).The differences in the total pump pressing times and total effecting times within 48 hours after operation between Group H,Group M and Group L were statistical significant(P0.05).Conclusion 1.5 μg /ml epidural Sufentanil pumped into the thoracic intervertebral spaces can be applied into the pain treatment after upper abdominal operation.The analgesic effect is satisfactory with little adverse effects.1.5 μg /ml epidural Sufentanil pumped into the lumbar intervertebral spaces can substitute for thoracic epidural analgesia as an alternative method in the pain treatment after upper abdominal operation.However,compared to the latter,the Sufentanil dosage is relatively high." @default.
- W2364522011 created "2016-06-24" @default.
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- W2364522011 date "2010-01-01" @default.
- W2364522011 modified "2023-09-23" @default.
- W2364522011 title "A Study of Epidural Analgesia Using Sufentanil at Different Puncture after Upper Abdominal Surgery" @default.
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