Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364539219> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2364539219 abstract "Objective To investigate the role of Bmi-1 in breast cancer tumorigenesis and development and its prognostic value.Methods Expression of Bmi-1 was detected in 38 samples of normal or common hyperplasia breast tissue(3 cases of normal breast tissue and 35 cases of common hyperplasia breast tissue),41 samples of atypical hyperplasia breast tissue,33 samples of breast carcinoma in situ(28 cases of intraductal carcinoma and 5 cases of carcinoma in situ) and 129 samples of invasive breast cancer with immunohisto-chemistry EnVision method.The relationships among Bmi-1 expression and clinic stage,hormone receptor status,menstruation status,axillary lymph node metastasis status,pathological type,HER-2 status,disease free survival and overall survival were also investigated.Results Expression of Bmi-1 in invasive breast cancer was stronger than that in breast carcinoma in situ,atypical hyperplasia breast tissue,normal or common hyperplasia breast tissue,showing statistical significance(P0.05);there was not significant difference between the Bmi-1 expression in breast carcinoma in situ and that in atypical hyperplasia breast tissue,but both expression was stronger than that in normal or common hyperplasia breast tissue with significant difference(P0.05);there were not relationships among the Bmi-1 expression and clinical stage,hormone receptor status,menstruation status,axillary lymph node metastasis status or pathological type(P0.05);the disease free survival of those patients with low Bmi-1 expression was better than those with stronger Bmi-1expression,but there was not significant difference in the overall survival.Multivariate analysis utilizing Cox regression analysis showed that Bmi-1 was not an independent prognosis biomarker.Conclusion Bmi-1 plays an important role in breast cancer tumorigenesis and development,and more researches should be done to identify its value for prognosis." @default.
- W2364539219 created "2016-06-24" @default.
- W2364539219 creator A5075728835 @default.
- W2364539219 date "2011-01-01" @default.
- W2364539219 modified "2023-09-28" @default.
- W2364539219 title "The role of Bmi-1 in tumorigenesis and development of breast cancer and its prognostic value" @default.
- W2364539219 hasPublicationYear "2011" @default.
- W2364539219 type Work @default.
- W2364539219 sameAs 2364539219 @default.
- W2364539219 citedByCount "0" @default.
- W2364539219 crossrefType "journal-article" @default.
- W2364539219 hasAuthorship W2364539219A5075728835 @default.
- W2364539219 hasConcept C121608353 @default.
- W2364539219 hasConcept C126322002 @default.
- W2364539219 hasConcept C142724271 @default.
- W2364539219 hasConcept C143998085 @default.
- W2364539219 hasConcept C207886595 @default.
- W2364539219 hasConcept C2775904963 @default.
- W2364539219 hasConcept C2777546739 @default.
- W2364539219 hasConcept C2777562237 @default.
- W2364539219 hasConcept C2779013556 @default.
- W2364539219 hasConcept C2779880527 @default.
- W2364539219 hasConcept C2780862961 @default.
- W2364539219 hasConcept C3018521938 @default.
- W2364539219 hasConcept C530470458 @default.
- W2364539219 hasConcept C555283112 @default.
- W2364539219 hasConcept C71924100 @default.
- W2364539219 hasConcept C84606932 @default.
- W2364539219 hasConceptScore W2364539219C121608353 @default.
- W2364539219 hasConceptScore W2364539219C126322002 @default.
- W2364539219 hasConceptScore W2364539219C142724271 @default.
- W2364539219 hasConceptScore W2364539219C143998085 @default.
- W2364539219 hasConceptScore W2364539219C207886595 @default.
- W2364539219 hasConceptScore W2364539219C2775904963 @default.
- W2364539219 hasConceptScore W2364539219C2777546739 @default.
- W2364539219 hasConceptScore W2364539219C2777562237 @default.
- W2364539219 hasConceptScore W2364539219C2779013556 @default.
- W2364539219 hasConceptScore W2364539219C2779880527 @default.
- W2364539219 hasConceptScore W2364539219C2780862961 @default.
- W2364539219 hasConceptScore W2364539219C3018521938 @default.
- W2364539219 hasConceptScore W2364539219C530470458 @default.
- W2364539219 hasConceptScore W2364539219C555283112 @default.
- W2364539219 hasConceptScore W2364539219C71924100 @default.
- W2364539219 hasConceptScore W2364539219C84606932 @default.
- W2364539219 hasLocation W23645392191 @default.
- W2364539219 hasOpenAccess W2364539219 @default.
- W2364539219 hasPrimaryLocation W23645392191 @default.
- W2364539219 hasRelatedWork W1997250785 @default.
- W2364539219 hasRelatedWork W2062486301 @default.
- W2364539219 hasRelatedWork W2148063353 @default.
- W2364539219 hasRelatedWork W2186711830 @default.
- W2364539219 hasRelatedWork W2348827152 @default.
- W2364539219 hasRelatedWork W2352744839 @default.
- W2364539219 hasRelatedWork W2360341731 @default.
- W2364539219 hasRelatedWork W2360355257 @default.
- W2364539219 hasRelatedWork W2362680759 @default.
- W2364539219 hasRelatedWork W2362772042 @default.
- W2364539219 hasRelatedWork W2367340689 @default.
- W2364539219 hasRelatedWork W2373238826 @default.
- W2364539219 hasRelatedWork W2374700658 @default.
- W2364539219 hasRelatedWork W2374975602 @default.
- W2364539219 hasRelatedWork W2385468300 @default.
- W2364539219 hasRelatedWork W2790993522 @default.
- W2364539219 hasRelatedWork W2897588803 @default.
- W2364539219 hasRelatedWork W3029099181 @default.
- W2364539219 hasRelatedWork W3099588315 @default.
- W2364539219 hasRelatedWork W3202111131 @default.
- W2364539219 isParatext "false" @default.
- W2364539219 isRetracted "false" @default.
- W2364539219 magId "2364539219" @default.
- W2364539219 workType "article" @default.