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- W2364540643 abstract "Objective: TO observe effects of acupuncture on hypoxia-ischemia cerebral palsy rats, and to study its underlying neurobiochemical mechanism.Method:Neonatal SD rats,7d old,were randomized into acupuncture group(acupuncture was given 24h after operation),model group and control group. Cerebral palsy model was established by occlusion of the left common carotid artery and inhalation of 8% oxygen plus 92% nitrogen.The forepaw-touching test(adhesive plaster tearing-off test) were measured and the expression of glial fibrillary acidic protein(GFAP) in the brain was assayed with immunohistochemical method.Result:The duration values for tearing off adhesive-plaster on 7d, 14d and 21d of acupuncture were markedly shorter than that of the model group(P0.05),suggesting functional improvement of the rats' forelimbs. Twenty-one days after operation, the number of GFAP immunoreaction(IR) strongly-positive neurons in the cerebral cortex, straiate body and hippocampus were the biggest in the model group, smaller in the acupuncture group and only very weakly IR-positive neurons were found in the control group. Conclusion: Acupuncture therapy may be used to treat cerebral palsy at the early stage.Acupuncture can reduce the astrocytic activation, which may contribute to the effect of acupuncture in improving the cerebral palsy." @default.
- W2364540643 created "2016-06-24" @default.
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- W2364540643 date "2005-01-01" @default.
- W2364540643 modified "2023-09-23" @default.
- W2364540643 title "Effects of acupunture on GFAP expression in asphyxial cerebral paralysis rats" @default.
- W2364540643 hasPublicationYear "2005" @default.
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