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- W2364550925 abstract "Objective To analyze the clinical and laboratorial features of neuropsychiatric systemic lupus erythematosus(NPSLE),and to find the risk factors of NPSLE.Methods In a retrospective case-control study,single and multi-factors Logistic regression analysis were used.Results 9.8%(98/1004)patients were diagnosed NPSLE.The most frequent NPSLE syndromes was seizure disorders(36.7%),followed by cerebralvascular disease(26.5%),and phycosis(18.4%).Abnormalities of brain CT /MRI were brain atrophy(20.6%),cerebral in farction(16.2%).Abnormal CSF test was noted in 36% patients,but lack of specificity.The cutaneous vasculitis lesion was significantly higher than the control patients,the anti-dsDNA and anti-SSA/Ro antibodies were significantly lower than the control patients.Conclusions 98(9.8%)patients were diagnosed NPSLE,which was rather lower compared with other pulblished data.Seizure disorder was the most frenquent manifestation,followed by cerebrovascular disease and psychosis.Establishment diagnosis of NPSLE should be derived from a careful analysis of clinical,imaging data and CSF data on a case-by-case basis.Cutaneous vasculitis was a high risk factor and predictor of NPSLE." @default.
- W2364550925 created "2016-06-24" @default.
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- W2364550925 date "2008-01-01" @default.
- W2364550925 modified "2023-09-25" @default.
- W2364550925 title "Analysis on clinical and laboratorial features related to neuropsychiatric lupus erythematosus" @default.
- W2364550925 hasPublicationYear "2008" @default.
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