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- W2364554008 abstract "Objective To evaluate the effects of imidapril and benazapril on peripheral blood pressure, central blood pressure and large artery function in patients with essential hypertension. Method We conducted a double blind, double imitation, randomized cross over trial of imidapril and benazapril in 30 hypertensive patients. Using the PWV Medical blood pressure analysis system the central blood pressure, augmentation index and carotid femoral pulse wave velocity were before and after 10 weeks of daily treatment with imidapril(5 to 10 mg) and benazapril(10 to 20 mg) deterimed. Result After 10 weeks of treatment, both peripheral blood pressure and central blood pressure were significant decreased. The elevated augmentation index and carotid femoral pulse wave velocity in hypertensive patients were significant decreased by imidapril and benazapril. Conclusion long acting ACEI imidapril and benazapril decrease peripheral and central blood pressure, reduce wave reflection and pulse wave velocity, and increase the distensibility of aorta. These vascular protective effects may be beneficial to the improvement outcomes in hypertensive patients." @default.
- W2364554008 created "2016-06-24" @default.
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- W2364554008 date "2002-01-01" @default.
- W2364554008 modified "2023-09-25" @default.
- W2364554008 title "Effects of Angiotensin Converting Enzyme Inhibitors on Large Artery Function in Patients with Essential Hypertension" @default.
- W2364554008 hasPublicationYear "2002" @default.
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